Radiation synergizes with antitumor activity of CD13-targeted tissue factor in a HT1080 xenograft model of human soft tissue sarcoma

BACKGROUND: Truncated tissue factor (tTF) retargeted by NGR-peptides to aminopeptidase N (CD13) in tumor vasculature is effective in experimental tumor therapy. tTF-NGR induces tumor growth inhibition in a variety of human tumor xenografts of different histology. To improve on the therapeutic effica...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Brand, Caroline, Greve, Burkhard, Bölling, Tobias, Eich, Hans T., Willich, Normann, Harrach, Saliha, Hintelmann, Heike, Lenz, Georg, Mesters, Rolf M., Kessler, Torsten, Schliemann, Christoph, Berdel, Wolfgang E., Schwöppe, Christian
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2020
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7034830/
https://ncbi.nlm.nih.gov/pubmed/32084238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0229271
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