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CRISPR/CAS9-based DNA damage response screens reveal gene-drug interactions
DNA damage response (DDR) is critically important for cell survival, genome maintenance, and its defect has been exploited therapeutically in cancer treatment. Many DDR-targeting agents have been generated and have entered the clinic and/or clinical trials. In order to provide a global and unbiased...
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| Vydáno v: | DNA Repair (Amst) |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7034363/ https://ncbi.nlm.nih.gov/pubmed/31991288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2020.102803 |
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