A Novel Model of Diabetic Complications: Adipocyte Mitochondrial Dysfunction Triggers Massive β-Cell Hyperplasia

Obesity-associated type 2 diabetes mellitus (T2DM) entails insulin resistance and loss of β-cell mass. Adipose tissue mitochondrial dysfunction is emerging as a key component in the etiology of T2DM. Identifying approaches to preserve mitochondrial function, adipose tissue integrity, and β-cell mass...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Diabetes
Autori principali: Kusminski, Christine M., Ghaben, Alexandra L., Morley, Thomas S., Samms, Ricardo J., Adams, Andrew C., An, Yu, Johnson, Joshua A., Joffin, Nolwenn, Onodera, Toshiharu, Crewe, Clair, Holland, William L., Gordillo, Ruth, Scherer, Philipp E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2020
Soggetti:
Metabolism
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7034182/
https://ncbi.nlm.nih.gov/pubmed/31882562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0327
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi