A Novel Model of Diabetic Complications: Adipocyte Mitochondrial Dysfunction Triggers Massive β-Cell Hyperplasia

Obesity-associated type 2 diabetes mellitus (T2DM) entails insulin resistance and loss of β-cell mass. Adipose tissue mitochondrial dysfunction is emerging as a key component in the etiology of T2DM. Identifying approaches to preserve mitochondrial function, adipose tissue integrity, and β-cell mass...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Diabetes
Päätekijät: Kusminski, Christine M., Ghaben, Alexandra L., Morley, Thomas S., Samms, Ricardo J., Adams, Andrew C., An, Yu, Johnson, Joshua A., Joffin, Nolwenn, Onodera, Toshiharu, Crewe, Clair, Holland, William L., Gordillo, Ruth, Scherer, Philipp E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Diabetes Association 2020
Aiheet:
Metabolism
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7034182/
https://ncbi.nlm.nih.gov/pubmed/31882562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0327
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