Drug-interactive mPEG-b-PLA-Phe(Boc) micelles enhance the tolerance and anti-tumor efficacy of docetaxel

Docetaxel (DTX) is one of the most promising chemotherapeutic agents for a variety of solid tumors. However, the clinical efficacy of the marketed formulation, Taxotere(®), is limited due to its poor aqueous solubility, side effects caused by the emulsifier, and low selective DTX distribution in viv...

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Bibliographische Detailangaben
Veröffentlicht in:Drug Deliv
Hauptverfasser: Gong, Feirong, Wang, Rongrong, Zhu, Zhengquan, Duan, Jiayao, Teng, Xin, Cui, Zhong-Kai
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7034090/
https://ncbi.nlm.nih.gov/pubmed/32003299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2020.1718245
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