Aspirin Reduces the Potentiating Effect of CD40L on Platelet Aggregation via Inhibition of Myosin Light Chain

BACKGROUND: Antiplatelet therapy with aspirin (acetylsalicylic acid [ASA]) is less efficient in some coronary patients, which increases their risk of developing thrombosis. Elevated blood levels of thromboinflammatory mediators, like soluble CD40L (sCD40L), may explain such variabilities. We hypothe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Am Heart Assoc
Prif Awduron: Kojok, Kevin, Mohsen, Mira, El Kadiry, Abed El Hakim, Mourad, Walid, Merhi, Yahye
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2020
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033871/
https://ncbi.nlm.nih.gov/pubmed/32009527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.013396
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