Aspirin Reduces the Potentiating Effect of CD40L on Platelet Aggregation via Inhibition of Myosin Light Chain

BACKGROUND: Antiplatelet therapy with aspirin (acetylsalicylic acid [ASA]) is less efficient in some coronary patients, which increases their risk of developing thrombosis. Elevated blood levels of thromboinflammatory mediators, like soluble CD40L (sCD40L), may explain such variabilities. We hypothe...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Am Heart Assoc
Auteurs principaux: Kojok, Kevin, Mohsen, Mira, El Kadiry, Abed El Hakim, Mourad, Walid, Merhi, Yahye
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033871/
https://ncbi.nlm.nih.gov/pubmed/32009527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.013396
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