Fc Receptor-Like 6 (FCRL6) Discloses Progenitor B Cell Heterogeneity That Correlates With Pre-BCR Dependent and Independent Pathways of Natural Antibody Selection

B-1a cells produce “natural” antibodies (Abs) to neutralize pathogens and clear neo self-antigens, but the fundamental selection mechanisms that shape their polyreactive repertoires are poorly understood. Here, we identified a B cell progenitor subset defined by Fc receptor-like 6 (FCRL6) expression...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Honjo, Kazuhito, Won, Woong-Jai, King, Rodney G., Ianov, Lara, Crossman, David K., Easlick, Juliet L., Shakhmatov, Mikhail A., Khass, Mohamed, Vale, Andre M., Stephan, Robert P., Li, Ran, Davis, Randall S.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033751/
https://ncbi.nlm.nih.gov/pubmed/32117244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00082
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