Validated UPLC-MS/MS method for the determination of tadalafil in human plasma and its application to a pharmacokinetic study

A simple, rapid, and reliable UPLC-MS/MS method was developed and validated for the determination of tadalafil in human plasma. The plasma samples were deproteinized with acetonitrile. Chromatographic separation was performed on a Shiseido C18 (100 × 2.1 mm, 2.7 µm) column with isocratic elution usi...

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Detalles Bibliográficos
Publicado en:Transl Clin Pharmacol
Main Authors: Kim, Kwang-Youl, Nam, Moonsuk, Kwon, Hyun-Jung, Kim, Kwang-Hyeon, Kang, Seung-Hyun, Kim, Sang-Il, Kim, Cheol-Woo, Cho, Sang-Heon
Formato: Artigo
Idioma:Inglês
Publicado: Korean Society for Clinical Pharmacology and Therapeutics 2017
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033536/
https://ncbi.nlm.nih.gov/pubmed/32095455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12793/tcp.2017.25.1.21
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