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Development of a UPLC-MS/MS method for the therapeutic monitoring of L-asparaginase
This study aimed to develop a UPLC-MS/MS method for determining plasma levels of L-aspartic acid and L-asparagine and the activity of L-asparaginase. L-aspartic acid, L-asparagine, and L-aspartic acid-2,3,3-d(3) were extracted from human plasma by protein precipitation with sulfosalicylic acid (30%,...
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| Publicado no: | Transl Clin Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Korean Society for Clinical Pharmacology and Therapeutics
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6989229/ https://ncbi.nlm.nih.gov/pubmed/32055563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12793/tcp.2018.26.3.134 |
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