Microglia control vascular architecture via a TGFβ1 dependent paracrine mechanism linked to tissue mechanics

Tissue microarchitecture and mechanics are important in development and pathologies of the Central Nervous System (CNS); however, their coordinating mechanisms are unclear. Here, we report that during colonization of the retina, microglia contacts the deep layer of high stiffness, which coincides wi...

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Publicat a:Nat Commun
Autors principals: Dudiki, Tejasvi, Meller, Julia, Mahajan, Gautam, Liu, Huan, Zhevlakova, Irina, Stefl, Samantha, Witherow, Conner, Podrez, Eugene, Kothapalli, Chandrasekhar R., Byzova, Tatiana V.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033106/
https://ncbi.nlm.nih.gov/pubmed/32080187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14787-y
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