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Cell type-specific profiling of protein-DNA interactions without cell isolation using Targeted DamID with next-generation sequencing

The ability to profile transcription and chromatin binding in a cell type-specific manner is a powerful approach for understanding cell fate specification and cellular function in multicellular organisms. We recently developed Targeted DamID (TaDa) to enable genome-wide, cell-type-specific profiling...

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Publicat a:Nat Protoc
Autors principals: Marshall, Owen J., Southall, Tony D., Brand, Andrea H.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032955/
https://ncbi.nlm.nih.gov/pubmed/27490632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2007.148
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