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Cell type-specific profiling of protein-DNA interactions without cell isolation using Targeted DamID with next-generation sequencing
The ability to profile transcription and chromatin binding in a cell type-specific manner is a powerful approach for understanding cell fate specification and cellular function in multicellular organisms. We recently developed Targeted DamID (TaDa) to enable genome-wide, cell-type-specific profiling...
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| 發表在: | Nat Protoc |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7032955/ https://ncbi.nlm.nih.gov/pubmed/27490632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2007.148 |
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