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Hantavirus inhibits apoptosis by preventing mitochondrial membrane potential loss through up-regulation of the pro-survival factor BCL-2

Hantaviruses, zoonotic RNA viruses belonging to the order Bunyavirales, cause two severe acute diseases in humans, hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). Hantavirus-infected patients show strong cytotoxic lymphocyte responses and hyperinflammation; howe...

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Bibliografiske detaljer
Udgivet i:PLoS Pathog
Main Authors: Solà-Riera, Carles, García, Marina, Ljunggren, Hans-Gustaf, Klingström, Jonas
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032725/
https://ncbi.nlm.nih.gov/pubmed/32032391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008297
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