Loss of Cell Membrane Integrity in Puumala Hantavirus-Infected Patients Correlates with Levels of Epithelial Cell Apoptosis and Perforin

Hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome are two diseases caused by hantaviruses. Capillary leakage is a hallmark of hantavirus infection. Pathogenic hantaviruses are not cytotoxic, but elevated levels of serum lactate dehydrogenase (LDH), indicative of cellular damage...

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Bibliographic Details
Main Authors: Klingström, Jonas, Hardestam, Jonas, Stoltz, Malin, Zuber, Bartek, Lundkvist, Åke, Linder, Stig, Ahlm, Clas
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563790/
https://ncbi.nlm.nih.gov/pubmed/16873286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00742-06
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