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Transglutaminase 2 mediates hypoxia-induced selective mRNA translation via polyamination of 4EBPs
Hypoxia selectively enhances mRNA translation despite suppressed mammalian target of rapamycin complex 1 activity, contributing to gene expression reprogramming that promotes metastasis and survival of cancer cells. Little is known about how this paradoxical control of translation occurs. Here, we r...
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| Publicado no: | Life Sci Alliance |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Life Science Alliance LLC
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7032569/ https://ncbi.nlm.nih.gov/pubmed/32075852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900565 |
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