Epigenetically quantified immune cells in salivary glands of Sjögren’s syndrome patients: a novel tool that detects robust correlations of T follicular helper cells with immunopathology

OBJECTIVE: To investigate whether epigenetic cell counting represents a novel method to quantify immune cells in salivary glands of patients with different forms of Sjögren’s and sicca syndrome and to capture immunopathology and potentially aid in diagnosis. METHODS: DNA from frozen salivary gland t...

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Detalles Bibliográficos
Publicado en:Rheumatology (Oxford)
Main Authors: Blokland, Sofie L M, van Vliet-Moret, Fréderique M, Hillen, Maarten R, Pandit, Aridaman, Goldschmeding, Roel, Kruize, Aike A, Bouma, Gerben, van Maurik, André, Olek, Sven, Hoffmueller, Ulrich, van Roon, Joel A G, Radstake, Timothy R D J
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
Assuntos:
Clinical Science
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032543/
https://ncbi.nlm.nih.gov/pubmed/31325310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kez268
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