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Double-layered osmotic pump controlled release tablets of actarit: In vitro and in vivo evaluation

The aim of the study was to develop actarit double-layered osmotic pump tablets to overcome the weak points of actarit common tablets, such as short half-life and large plasma concentration fluctuations. Single factor experiment and orthogonal test were applied to optimize the formulation; the pharm...

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Detalhes bibliográficos
Publicado no:Asian J Pharm Sci
Main Authors: Li, Yuenan, Pan, Hao, Duan, Hongliang, Chen, Jianting, Zhu, Zhihong, Fan, Jingxin, Li, Pingfei, Yang, Xinggang, Pan, Weisan
Formato: Artigo
Idioma:Inglês
Publicado em: Shenyang Pharmaceutical University 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032193/
https://ncbi.nlm.nih.gov/pubmed/32104464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2018.05.009
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