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Inclusion complex of tamibarotene with hydroxypropyl-β-cyclodextrin: Preparation, characterization, in-vitro and in-vivo evaluation

The goal of this study was to improve the solubility and oral bioavailability of tamibarotene by complexing it with hydroxypropyl-β-cyclodextrin (HP-β-CD). The inclusion complex of tamibarotene with hydroxypropyl-β-cyclodextrin (Am80-HP-β-CD) was prepared through a freeze-drying method at the mole r...

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Publicado en:Asian J Pharm Sci
Main Authors: Yang, Ying, Gao, Jinhua, Ma, Xiaoyu, Huang, Guihua
Formato: Artigo
Idioma:Inglês
Publicado: Shenyang Pharmaceutical University 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032095/
https://ncbi.nlm.nih.gov/pubmed/32104329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2016.08.009
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