Combretastatin A4/poly(L-glutamic acid)-graft-PEG conjugates self-assembled to nanoparticles

Combretastatin A4 (CA4) possesses varying ability to cause vascular disruption in tumors, while the short half-life, low water solubility and deactivation of many CA4 analogs during storage limited its antitumor efficacy and drug stability. A novel macromolecular conjugate of CA4 (CA4-PL) was synthe...

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Enregistré dans:
Détails bibliographiques
Publié dans:Asian J Pharm Sci
Auteurs principaux: Ou, Yang, Tang, Zhao-hui, Sun, Lu, Yu, Hai-yang, Li, Jia, Zhao, Mei-hui, Xu, Hui
Format: Artigo
Langue:Inglês
Publié: Shenyang Pharmaceutical University 2018
Sujets:
Short Communication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032092/
https://ncbi.nlm.nih.gov/pubmed/32104392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2017.10.001
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