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Effect of Osmolytes on Conformational Behavior of Intrinsically Disordered Protein α-Synuclein

α-Synuclein is an intrinsically disordered protein whose function in a healthy brain is poorly understood. It is genetically and neuropathologically linked to Parkinson’s disease (PD). PD is manifested after the accumulation of plaques of α-synuclein aggregates in the brain cells. Aggregates of α-sy...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Jahan, Ishrat, Nayeem, Shahid M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031737/
https://ncbi.nlm.nih.gov/pubmed/31699336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.09.046
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