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Associations between brain inflammatory profiles and human neuropathology are altered based on apolipoprotein E ε4 genotype

Alzheimer disease (AD) is a chronic neurodegenerative disease with a multitude of contributing genetic factors, many of which are related to inflammation. The apolipoprotein E (APOE) ε4 allele is the most common genetic risk factor for AD and is related to a pro-inflammatory state. To test the hypot...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Friedberg, Jacob S., Aytan, Nurgul, Cherry, Jonathan D., Xia, Weiming, Standring, Oliver J., Alvarez, Victor E., Nicks, Raymond, Svirsky, Sarah, Meng, Gaoyuan, Jun, Gyungah, Ryu, Hoon, Au, Rhoda, Stein, Thor D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031423/
https://ncbi.nlm.nih.gov/pubmed/32076055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59869-5
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