Associations between brain inflammatory profiles and human neuropathology are altered based on apolipoprotein E ε4 genotype

Alzheimer disease (AD) is a chronic neurodegenerative disease with a multitude of contributing genetic factors, many of which are related to inflammation. The apolipoprotein E (APOE) ε4 allele is the most common genetic risk factor for AD and is related to a pro-inflammatory state. To test the hypot...

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Vydáno v:Sci Rep
Hlavní autoři: Friedberg, Jacob S., Aytan, Nurgul, Cherry, Jonathan D., Xia, Weiming, Standring, Oliver J., Alvarez, Victor E., Nicks, Raymond, Svirsky, Sarah, Meng, Gaoyuan, Jun, Gyungah, Ryu, Hoon, Au, Rhoda, Stein, Thor D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031423/
https://ncbi.nlm.nih.gov/pubmed/32076055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59869-5
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