LATS kinase–mediated CTCF phosphorylation and selective loss of genomic binding

Chromatin topological organization is instrumental in gene transcription. Gene-enhancer interactions are accommodated in the same CTCF-mediated insulated neighborhoods. However, it remains poorly understood whether and how the 3D genome architecture is dynamically restructured by external signals. H...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Luo, Huacheng, Yu, Qin, Liu, Yang, Tang, Ming, Liang, Mingwei, Zhang, Dingpeng, Xiao, Tsan Sam, Wu, Lizi, Tan, Ming, Ruan, Yijun, Bungert, Jörg, Lu, Jianrong
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7030924/
https://ncbi.nlm.nih.gov/pubmed/32128389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaw4651
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