Spectroscopic and molecular docking studies reveal binding characteristics of nazartinib (EGF816) to human serum albumin

The interactions of novel anti-cancer therapeutic agents with the different plasma and tissue components, specifically serum albumins, have lately gained considerable attention due to the significant influence of such interactions on the pharmacokinetics and/or -dynamics of this important class of t...

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Bibliographische Detailangaben
Veröffentlicht in:R Soc Open Sci
Hauptverfasser: Almehizia, Abdulrahman A., AlRabiah, Haitham, Bakheit, Ahmed H., Hassan, Eman S. G., Herqash, Rashed N., Abdelhameed, Ali Saber
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society 2020
Schlagworte:
Chemistry
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029911/
https://ncbi.nlm.nih.gov/pubmed/32218978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.191595
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