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Spectroscopic and molecular docking studies reveal binding characteristics of nazartinib (EGF816) to human serum albumin

The interactions of novel anti-cancer therapeutic agents with the different plasma and tissue components, specifically serum albumins, have lately gained considerable attention due to the significant influence of such interactions on the pharmacokinetics and/or -dynamics of this important class of t...

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Publicado en:R Soc Open Sci
Main Authors: Almehizia, Abdulrahman A., AlRabiah, Haitham, Bakheit, Ahmed H., Hassan, Eman S. G., Herqash, Rashed N., Abdelhameed, Ali Saber
Formato: Artigo
Idioma:Inglês
Publicado: The Royal Society 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029911/
https://ncbi.nlm.nih.gov/pubmed/32218978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.191595
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