Integrated proteogenomic approach identifying a protein signature of COPD and a new splice variant of SORBS1

Translation of genomic alterations to protein changes in chronic obstructive pulmonary disease (COPD) is largely unexplored. Using integrated proteomic and RNA sequencing analysis of COPD and control lung tissues, we identified a protein signature in COPD characterised by extracellular matrix change...

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Detalhes bibliográficos
Publicado no:Thorax
Main Authors: Brandsma, Corry-Anke, Guryev, Victor, Timens, Wim, Ciconelle, Ana, Postma, Dirkje S, Bischoff, Rainer, Johansson, Maria, Ovchinnikova, Ekaterina S, Malm, Johan, Marko-Varga, Gyorgy, Fehniger, Thomas E, van den Berge, Maarten, Horvatovich, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029225/
https://ncbi.nlm.nih.gov/pubmed/31937552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2019-213200
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