Opportunities and challenges in the therapeutic activation of human energy expenditure and thermogenesis to manage obesity

The current obesity pandemic results from a physiological imbalance in which energy intake chronically exceeds energy expenditure (EE), and prevention and treatment strategies remain generally ineffective. Approaches designed to increase EE have been informed by decades of experiments in rodent mode...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Chen, Kong Y., Brychta, Robert J., Abdul Sater, Zahraa, Cassimatis, Thomas M., Cero, Cheryl, Fletcher, Laura A., Israni, Nikita S., Johnson, James W., Lea, Hannah J., Linderman, Joyce D., O'Mara, Alana E., Zhu, Kenneth Y., Cypess, Aaron M.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2020
Subjects:
JBC Reviews
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029124/
https://ncbi.nlm.nih.gov/pubmed/31914415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV119.007363
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