Opportunities and challenges in the therapeutic activation of human energy expenditure and thermogenesis to manage obesity

The current obesity pandemic results from a physiological imbalance in which energy intake chronically exceeds energy expenditure (EE), and prevention and treatment strategies remain generally ineffective. Approaches designed to increase EE have been informed by decades of experiments in rodent mode...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chen, Kong Y., Brychta, Robert J., Abdul Sater, Zahraa, Cassimatis, Thomas M., Cero, Cheryl, Fletcher, Laura A., Israni, Nikita S., Johnson, James W., Lea, Hannah J., Linderman, Joyce D., O'Mara, Alana E., Zhu, Kenneth Y., Cypess, Aaron M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
JBC Reviews
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029124/
https://ncbi.nlm.nih.gov/pubmed/31914415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV119.007363
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