Immunochip meta-analysis in European and Argentinian populations identifies two novel genetic loci associated with celiac disease

Celiac disease (CeD) is a common immune-mediated disease of the small intestine that is triggered by exposure to dietary gluten. While the HLA locus plays a major role in disease susceptibility, 39 non-HLA loci were also identified in a study of 24,269 individuals. We now build on this earlier study...

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Vydáno v:Eur J Hum Genet
Hlavní autoři: Ricaño-Ponce, Isis, Gutierrez-Achury, Javier, Costa, Ana Florencia, Deelen, Patrick, Kurilshikov, Alexander, Zorro, Maria Magdalena, Platteel, Mathieu, van der Graaf, Adriaan, Sanna, Serena, Daffra, Oscar, Zhernakova, Alexandra, Fu, Jingyuan, Trynka, Gosia, Smecuol, Edgardo, Niveloni, Sonia Isabel, Bai, Julio Cesar, Kumar, Vinod, Wijmenga, Cisca
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028987/
https://ncbi.nlm.nih.gov/pubmed/31591516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-019-0520-4
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