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Aminooxyacetic acid attenuates post‐infarct cardiac dysfunction by balancing macrophage polarization through modulating macrophage metabolism in mice

Excessive activation of pro‐inflammatory M1 macrophages following acute myocardial infarction (MI) aggravates adverse cardiac remodelling and heart dysfunction. There are two break points in the tricarboxylic acid cycle of M1 macrophages, and aspartate‐arginosuccinate shunt compensates them. Aminoox...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Cell Mol Med
Päätekijät: Zhao, Pei, Zhou, Wenjing, Zhang, Yanxia, Li, Jingjing, Zhao, Ye, Pan, Lihua, Shen, Zhenya, Chen, Weiqian, Hui, Jie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028849/
https://ncbi.nlm.nih.gov/pubmed/31930778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14972
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