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Identification of a Novel Deactivating Small-Molecule Compound for Fibrogenic Hepatic Stellate Cells
BACKGROUND: Liver fibrosis progresses to decompensated liver cirrhosis, for which medical needs remain unmet. We recently developed IC-2, a small-molecule compound that suppresses Wnt/β-catenin signaling, and found that IC-2 also suppresses liver fibrosis. In this study, we performed three-step scre...
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| Izdano u: | Yonago Acta Med |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
YAM
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7028531/ https://ncbi.nlm.nih.gov/pubmed/32158337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.33160/yam.2020.02.013 |
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