Human mesenchymal stem cell-engineered hepatic cell sheets accelerate liver regeneration in mice

Mesenchymal stem cells (MSCs) are an attractive cell source for cell therapy. Based on our hypothesis that suppression of Wnt/β-catenin signal enhances hepatic differentiation of human MSCs, we developed human mesenchymal stem cell-engineered hepatic cell sheets by a small molecule compound. Screeni...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Itaba, Noriko, Matsumi, Yoshiaki, Okinaka, Kaori, Ashla, An Afida, Kono, Yohei, Osaki, Mitsuhiko, Morimoto, Minoru, Sugiyama, Naoyuki, Ohashi, Kazuo, Okano, Teruo, Shiota, Goshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639852/
https://ncbi.nlm.nih.gov/pubmed/26553591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16169
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