Prenatal intermittent hypoxia sensitizes the laryngeal chemoreflex, blocks serotoninergic shortening of the reflex, and reduces 5-HT(3) receptor binding in the NTS in anesthetized rat pups

We tested the hypothesis that exposure to intermittent hypoxia (IH) during pregnancy would prolong the laryngeal chemoreflex (LCR) and diminish the capacity of serotonin (5-hydroxytryptamine; 5-HT) to terminate the LCR. Prenatal exposure to IH was associated with significant prolongation of the LCR...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Donnelly, William T., Haynes, Robin L., Commons, Kathryn G., Erickson, Drexel, Panzini, Chris M., Xia, Luxi, Han, Q. Joyce, Leiter, J.C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028519/
https://ncbi.nlm.nih.gov/pubmed/31887303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2019.113166
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