Prenatal intermittent hypoxia sensitizes the laryngeal chemoreflex, blocks serotoninergic shortening of the reflex, and reduces 5-HT(3) receptor binding in the NTS in anesthetized rat pups

We tested the hypothesis that exposure to intermittent hypoxia (IH) during pregnancy would prolong the laryngeal chemoreflex (LCR) and diminish the capacity of serotonin (5-hydroxytryptamine; 5-HT) to terminate the LCR. Prenatal exposure to IH was associated with significant prolongation of the LCR...

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Publicado en:Exp Neurol
Main Authors: Donnelly, William T., Haynes, Robin L., Commons, Kathryn G., Erickson, Drexel, Panzini, Chris M., Xia, Luxi, Han, Q. Joyce, Leiter, J.C.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028519/
https://ncbi.nlm.nih.gov/pubmed/31887303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2019.113166
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