Prenatal intermittent hypoxia sensitizes the laryngeal chemoreflex, blocks serotoninergic shortening of the reflex, and reduces 5-HT(3) receptor binding in the NTS in anesthetized rat pups

We tested the hypothesis that exposure to intermittent hypoxia (IH) during pregnancy would prolong the laryngeal chemoreflex (LCR) and diminish the capacity of serotonin (5-hydroxytryptamine; 5-HT) to terminate the LCR. Prenatal exposure to IH was associated with significant prolongation of the LCR...

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Gepubliceerd in:Exp Neurol
Hoofdauteurs: Donnelly, William T., Haynes, Robin L., Commons, Kathryn G., Erickson, Drexel, Panzini, Chris M., Xia, Luxi, Han, Q. Joyce, Leiter, J.C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028519/
https://ncbi.nlm.nih.gov/pubmed/31887303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2019.113166
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