Persistently increased cell-free DNA concentrations only modestly contribute to outcome and host response in sepsis survivors with chronic critical illness

BACKGROUND: Although early survival from sepsis has improved with timely resuscitation and source control, survivors frequently experience persistent inflammation and develop chronic critical illness (CCI). We examined whether increased copy number of endogenous alarmins, mitochondrial DNA (mtDNA),...

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Bibliographic Details
Published in:Surgery
Main Authors: Hawkins, Russell B., Stortz, Julie A., Holden, David C., Wang, Zhongkai, Raymond, Steven L., Cox, Michael C., Brakenridge, Scott C., Moore, Frederick A., Moldawer, Lyle L., Efron, Philip A.
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028489/
https://ncbi.nlm.nih.gov/pubmed/31898953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2019.11.018
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