Persistently increased cell-free DNA concentrations only modestly contribute to outcome and host response in sepsis survivors with chronic critical illness

BACKGROUND: Although early survival from sepsis has improved with timely resuscitation and source control, survivors frequently experience persistent inflammation and develop chronic critical illness (CCI). We examined whether increased copy number of endogenous alarmins, mitochondrial DNA (mtDNA),...

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Publicado en:Surgery
Main Authors: Hawkins, Russell B., Stortz, Julie A., Holden, David C., Wang, Zhongkai, Raymond, Steven L., Cox, Michael C., Brakenridge, Scott C., Moore, Frederick A., Moldawer, Lyle L., Efron, Philip A.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028489/
https://ncbi.nlm.nih.gov/pubmed/31898953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2019.11.018
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