Persistently increased cell-free DNA concentrations only modestly contribute to outcome and host response in sepsis survivors with chronic critical illness

BACKGROUND: Although early survival from sepsis has improved with timely resuscitation and source control, survivors frequently experience persistent inflammation and develop chronic critical illness (CCI). We examined whether increased copy number of endogenous alarmins, mitochondrial DNA (mtDNA),...

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Detalhes bibliográficos
Publicado no:Surgery
Main Authors: Hawkins, Russell B., Stortz, Julie A., Holden, David C., Wang, Zhongkai, Raymond, Steven L., Cox, Michael C., Brakenridge, Scott C., Moore, Frederick A., Moldawer, Lyle L., Efron, Philip A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028489/
https://ncbi.nlm.nih.gov/pubmed/31898953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2019.11.018
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