Efficacy and Toxicity of Reduced vs. Standard Dose Pegylated Asparaginase in Adults with Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia

Incorporation of asparaginase (ASNase) and pegylated asparaginase (PEG-ASP) into pediatric-inspired regimens for adults with acute lymphoblastic leukemia (ALL) has led to improved treatment outcomes albeit with increased toxicities. This study compared the efficacy and safety of the Children’s Oncol...

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Publicat a:Leuk Lymphoma
Autors principals: Derman, Benjamin A, Streck, Mitchell, Wynne, Joseph, Christ, Trevor N, Curran, Emily, Stock, Wendy, Knoebel, Randall W
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028458/
https://ncbi.nlm.nih.gov/pubmed/31680584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2019.1680839
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