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Asparaginase (native ASNase or pegylated ASNase) in the treatment of acute lymphoblastic leukemia

The discovery of the tumor-inhibitory properties of asparaginase (ASNase) began in the early 1950s with the observation that guinea pig serum-treated lymphoma-bearing mice underwent rapid and often complete regression. About 4000 cases of acute lymphoblastic leukemia (ALL) are diagnosed very year in...

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Bibliographic Details
Main Authors: Avramis, Vassilios I, Tiwari, Prakash Nidhi
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2426805/
https://ncbi.nlm.nih.gov/pubmed/17717965
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