High Incidence of Symptomatic Hyperammonemia in Children with Acute Lymphoblastic Leukemia Receiving Pegylated Asparaginase

Asparaginase is a mainstay of treatment of childhood acute lymphoblastic leukemia. Pegylation of asparaginase extends its biological half-life and has been introduced in the newest treatment protocols aiming to further increase treatment success. Hyperammonemia is a recognized side effect of asparag...

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Detalhes bibliográficos
Main Authors: Heitink-Pollé, Katja M J, Prinsen, Berthil H. C. M. T., de Koning, Tom J, van Hasselt, Peter M, Bierings, Marc B
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575055/
https://ncbi.nlm.nih.gov/pubmed/23430503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/8904_2012_156
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