Proteomic modulation in breast tumors after metformin exposure: results from a “window of opportunity” trial

PURPOSE: Reverse Phase Protein Array (RPPA) is a high-throughput antibody-based technique to assess cellular protein activity. The goal of this study was to assess protein marker changes by RPPA in tumor tissue from a pre-surgical metformin trial in women with operable breast cancer (BC). METHODS: I...

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Detalhes bibliográficos
Publicado no:Clin Transl Oncol
Main Authors: Kalinsky, K., Zheng, T., Hibshoosh, H., Du, X., Mundi, P., Yang, J., Refice, S., Feldman, S. M., Taback, B., Connolly, E., Crew, K. D., Maurer, M. A., Hershman, D. L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028354/
https://ncbi.nlm.nih.gov/pubmed/27305912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12094-016-1521-1
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