3-Bromopyruvate alleviates the development of monocrotaline-induced rat pulmonary arterial hypertension by decreasing aerobic glycolysis, inducing apoptosis, and suppressing inflammation

BACKGROUND: Pulmonary arterial hypertension (PH) is a progressive disease with limited therapeutic options, ultimately leading to right heart failure and death. Recent findings indicate the role of the Warburg effect (aerobic glycolysis) in the development of PH. However, the effect of the glycolysi...

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Vydáno v:Chin Med J (Engl)
Hlavní autoři: Liu, Jie, Wang, Wang, Wang, Lei, Qi, Xian-Mei, Sha, Yu-Hui, Yang, Ting
Médium: Artigo
Jazyk:Inglês
Vydáno: Wolters Kluwer Health 2020
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028200/
https://ncbi.nlm.nih.gov/pubmed/31923104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CM9.0000000000000577
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