One piece of the puzzle: Population pharmacokinetics of FVIII during perioperative Haemate P(®)/Humate P(®) treatment in von Willebrand disease patients

INTRODUCTION: Many patients with von Willebrand disease (VWD) are treated on demand with von Willebrand factor and factor VIII (FVIII) containing concentrates present with VWF and/or FVIII plasma levels outside set target levels. This carries a risk for bleeding and potentially for thrombosis. Devel...

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Udgivet i:J Thromb Haemost
Main Authors: de Jager, Nico C. B., Bukkems, Laura H., Heijdra, Jessica M., Hazendonk, Carolien H. C. A. M., Fijnvandraat, Karin, Meijer, Karina, Eikenboom, Jeroen, Laros ‐ van Gorkom, Britta A. P., Leebeek, Frank W. G., Cnossen, Marjon H., Mathôt, Ron A. A., Collins, P. W.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
HAEMOSTASIS
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028136/
https://ncbi.nlm.nih.gov/pubmed/31557387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14652
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