Heart Failure Endpoints in Cardiovascular Outcome Trials of SGLT2 inhibitors in Patients with Type 2 Diabetes: A Critical Evaluation of Clinical and Regulatory Issues

Following regulatory guidance set forth in 2008 by the United States Food and Drug Administration (FDA) for new drugs for type 2 diabetes mellitus, many large randomized controlled trials have been conducted with the primary goal of assessing the safety of antihyperglycemic medications on the primar...

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Publicado no:Circulation
Main Authors: Butler, Javed, Packer, Milton, Greene, Stephen J., Fiuzat, Mona, Anker, Stefan D., Anstrom, Kevin J., Carson, Peter E., Cooper, Lauren B., Fonarow, Gregg C., Hernandez, Adrian F., Januzzi, James L., Jessup, Mariell, Kalyani, Rita R., Kaul, Sanjay, Kosiborod, Mikhail, Lindenfeld, JoAnn, McGuire, Darren K., Sabatine, Marc S., Solomon, Scott D., Teerlink, John R., Vaduganathan, Muthiah, Yancy, Clyde W., Stockbridge, Norman, O’Connor, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7027964/
https://ncbi.nlm.nih.gov/pubmed/31841369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.119.042155
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