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Reassessing the Role of Surrogate Endpoints in Drug Development for Heart Failure

With few notable exceptions, drug development for heart failure (HF) has become progressively more challenging and there remain no definitively proven therapies for patients with acute HF or HF with preserved ejection fraction. Inspection of temporal trends suggests an increasing rate of disagreemen...

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Bibliografische gegevens
Gepubliceerd in:Circulation
Hoofdauteurs: Greene, Stephen J., Mentz, Robert J., Fiuzat, Mona, Butler, Javed, Solomon, Scott D., Ambrosy, Andrew P., Mehta, Cyrus, Teerlink, John R., Zannad, Faiez, O’Connor, Christopher M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205720/
https://ncbi.nlm.nih.gov/pubmed/30354535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.118.034668
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