A pilot study of preproinsulin peptides reactivity in Chinese patients with type 1 diabetes

BACKGROUND: The aim of our study is to investigate whether preproinsulin (PPI) could trigger a proinflammatory CD4(+) T cell response in Chinese patients with type 1 diabetes (T1D). METHODS: Peripheral blood mononuclear cells were stimulated by a pool of 13 PPI peptides. Additional five PPI peptides...

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Publicado en:Diabetes Metab Res Rev
Autores principales: Xian, Yingxin, Xu, Haixia, Gao, Yifang, Yan, Jinhua, Lv, Jing, Ren, Wenqian, Huang, Qianwen, Jiang, Ziyu, Xu, Fen, Yao, Bin, Weng, Jianping
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7027544/
https://ncbi.nlm.nih.gov/pubmed/31655017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dmrr.3228
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