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Mechanistic Insights into Specific G Protein Interactions with Adenosine Receptors

Coupling between G-protein-coupled receptors (GPCRs) and the G proteins is a key step in cellular signaling. Despite extensive experimental and computational studies, the mechanism of specific GPCR-G protein coupling remains poorly understood. This has greatly hindered effective drug design of GPCRs...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Wang, Jinan, Miao, Yinglong
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7026936/
https://ncbi.nlm.nih.gov/pubmed/31283874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b04867
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