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Mechanistic Insights into Specific G Protein Interactions with Adenosine Receptors
Coupling between G-protein-coupled receptors (GPCRs) and the G proteins is a key step in cellular signaling. Despite extensive experimental and computational studies, the mechanism of specific GPCR-G protein coupling remains poorly understood. This has greatly hindered effective drug design of GPCRs...
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| Pubblicato in: | J Phys Chem B |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7026936/ https://ncbi.nlm.nih.gov/pubmed/31283874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b04867 |
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