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Protect-seq: genome-wide profiling of nuclease inaccessible domains reveals physical properties of chromatin

In metazoan cell nuclei, heterochromatin constitutes large chromatin domains that are in close contact with the nuclear lamina. These heterochromatin/lamina-associated domains (LADs) domains are difficult to profile and warrants a simpler and direct method. Here we report a new method, Protect-seq,...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Spracklin, George, Pradhan, Sriharsa
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7026637/
https://ncbi.nlm.nih.gov/pubmed/31819993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1150
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