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Direct observation of damage clustering in irradiated DNA with atomic force microscopy

Ionizing radiation produces clustered DNA damage that contains two or more lesions in 10–20 bp. It is believed that the complexity of clustered damage (i.e., the number of lesions per damage site) is related to the biological severity of ionizing radiation. However, only simple clustered damage cont...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Xu, Xu, Nakano, Toshiaki, Tsuda, Masataka, Kanamoto, Ryota, Hirayama, Ryoichi, Uzawa, Akiko, Ide, Hiroshi
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7026632/
https://ncbi.nlm.nih.gov/pubmed/31840169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1159
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