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Chromosomal origin of replication coordinates logically distinct types of bacterial genetic regulation

For a long time it has been hypothesized that bacterial gene regulation involves an intricate interplay of the transcriptional regulatory network (TRN) and the spatial organization of genes in the chromosome. Here we explore this hypothesis both on a structural and on a functional level. On the stru...

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Detalhes bibliográficos
Publicado no:NPJ Syst Biol Appl
Main Authors: Kosmidis, Kosmas, Jablonski, Kim Philipp, Muskhelishvili, Georgi, Hütt, Marc-Thorsten
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7026169/
https://ncbi.nlm.nih.gov/pubmed/32066730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-020-0124-1
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